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KMID : 1009020170150030288
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Clinical Psychopharmacology and Neuroscience
2017 Volume.15 No. 3 p.288 ~ p.291
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Five Month-Persistent Extrapyramidal Symptoms following a Single Injection of Paliperidone Palmitate: A Case Report
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Jang Seo-Young
Woo Jung-Min
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Abstract
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Long-acting injectable (LAI) antipsychotics are useful in the treatments for schizophrenic patients with poor adherence due to their maintaining feature of therapeutic plasma level without daily administrations. However, their long-lasting property can cause complicated problems such as a long-lasting side effect. We report a patient who experienced LAI-induced extrapyramidal symptoms (EPSs) for 5 months after a single injection. During that period, every trial to ameliorate this condition turned out to be a failure. The 3-month formulation of paliperidone palmitate is now close at hand. We have to be aware of possible long-lasting adverse events and confirm the tolerability to LAI before use.
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KEYWORD
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Long-acting injectable antipsychotics, Paliperidone palmitate, Extrapyramidal symptoms, Schizophrenia
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